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publications

2024

Griffin C. and Saint-Jeannet J-P. (2024). In vitro modeling of cranial placode differentiation: recent advances, challenges and perspectives. Dev. Biol. 506, 20-30.

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2023

Juraver-Geslin* H., Devotta* A. and Saint-Jeannet J-P. (2023). Developmental roles of natriuretic peptides and their receptors. Cells & Dev. 176, 203878.

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Raghavan* R., Coppola* U., Wu* Y., Ihewulezi* C., Negrón-Piñero L.J, Maguire JE., Hong J., Cunningham M., Kim HJ., Albert TJ., Ali A.M., Saint-Jeannet J-P., Ristoratore F., Dahia C. and Di Gregorio A. (2023). Gene expression in notochord and nuclei pulposi: a study of gene families across the chordate phylum. BMC Ecology & Evolution, 23:63.

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Gouignard N., Bibonne A., Mata J., Bajanca F., Berki B.A., Barriga E., Saint-Jeannet J-P. and Theveneau E. (2023). Paracrine regulation of neural crest EMT by placodal MMP28. PLOS Biology, 21(8): e3002261

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Devotta* A., Juraver-Geslin* H., Griffin C. and Saint-Jeannet J-P. (2023). Npr3 regulates neural crest and cranial placode progenitors formation through its dual function as clearance and signaling receptor. eLife, 2023;12:e84036.

 

Stottmann R.W., Harris, M.P., Merrill A.E., Saint-Jeannet J-P. and Clouthier, D.E., (2023). The Society for Craniofacial Genetics and Developmental Biology 45th Annual Meeting. Am. J. Med. Genet. Part A., 191, 1-9.

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2022

Park B-Y., Tachi-Duprat M., Ihewulezi C., Devotta A. and Saint-Jeannet J-P. (2022). The core splicing factors EFTUD2, SNRPB and TXNL4a are essential for neural crest and craniofacial development. J. Dev. Biol. 10, 29.

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Wu* Y., Devotta* A., Jose-Edwards* D.S., Kugler J.E., Negrón-Piñero L.J., Braslavskaya K., Addy J., Saint-Jeannet J-P. and Di Gregorio A. (2022). Cross-regulation between Xbp1 and Brachyury uncovers an evolutionarily conserved subcircuit of the notochord gene regulatory network. eLife, 2022;11:e73992.

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Brugmann S.A., Merrill A.E., Saint-Jeannet J-P., Stottmann R.W. and Clouthier, D.E., (2022). The Society for Craniofacial Genetics and Developmental Biology 44th Annual Meeting. Am. J. Med. Genet. Part A. 188, 1-9.

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Dubey A. and Saint-Jeannet J-P. (2022). Anterior patterning genes induced by Zic1 are sensitive to retinoic acid and its metabolite, 4-oxo-RA. Dev. Dyn. 2022; 251:498–512.

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2021

Ihewulezi C. and Saint-Jeannet J-P. (2021). Function of chromatin modifier Hmgn1 in neural crest and craniofacial development. Genesis 2021; 59:e23447.

 

Timberlake A.T., Griffin C., Heike C.L., Hing A.V., Cunningham M.L., Chitayat D., Davis M.R., Doust S.J., Drake A.F., Duenas-Roque M.M., Goldblatt J., Gustafson J., Hurtado-Villa P., Johns A., Karp N., Laing N.G., Magee L., University of Washington Center for Mendelian Genomics, Mullegama S.V., Pachajoa H., Porras-Hurtado G.L., Schnur R., Slee J., Singer S.L., Staffenberg D.A., Timms A.E., Wise C.A., Zarante I., Saint-Jeannet J-P. and Luquetti L.V. (2021). Haploinsufficiency of SF3B2 causes craniofacial microsomia. Nat. Commun. 12, 4680 doi:10.1038/s41467-021-24852-9.

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Dubey A., Yu J., Liu T., Kane M. A. and Saint-Jeannet J-P. (2021). Retinoic acid production, regulation, and containment through Zic1, Pitx2c and Cyp26c1 control cranial placode specification. Development, 148, dev193227. doi:10.1242/dev.193227.

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Maharana S.K. and Saint-Jeannet J-P. (2021). Molecular mechanisms of hearing loss in Nager syndrome. Dev. Biol. 476, 200-208.

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Saint-Jeannet J-P, Blader P. and Taneyhill L. (2021). Editorial: Cranial placodes and neural crest interactions in craniofacial development. Front. Physiol. 12:681397.

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Saint-Jeannet J-P.(2021). Editorial - genesis: full speed ahead into the next decade of developmental genetics research. Genesis. 2021;59:e23400.

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Brugmann S.A., Clouthier, D.E., Saint-Jeannet J-P., Taneyhill L. A., and Moody S. A. (2021). The Society for Craniofacial Genetics and Developmental Biology 43rdAnnual Meeting. Am. J. Med. Genet. Part A.2021; 1–8.

 

2020

Griffin C. and Saint-Jeannet J-P. (2020). Spliceosomopathies: diseases and mechanisms. Dev. Dyn., 249, 1038-1046.

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Gouignard N., Theveneau E. and Saint-Jeannet J-P. (2020). Dynamic expression of MMP28 during cranial morphogenesis. Phil. Trans. R. Soc. B,75, 20190559.

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Eisenhoffer G.T. Jr., Clouthier D., Cox T., Saint-Jeannet J-P., Taneyhill L.A., Trainor P.A. and Moody S.A. (2020). The Society for Craniofacial Genetics and Developmental Biology 42nd Annual Meeting. Am. J. Med. Genet. Part A.2020; 1–7.

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2018

Devotta A., Hong C-S. and Saint-Jeannet J-P. (2018). Dkk2 promotes neural crest specification by activating Wnt/β-catenin signaling in a GSK3β independent manner. eLife2018;7:e34404.

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Creuzet S. and Saint-Jeannet J-P. (2018). Preface: Celebrating 150 years of neural crest research. Genesis. 2018;56:e23236. 

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Alkobtawi M., Ray H., Barriga E. H., Moreno M., Kerney R., Monsoro-Burq A-H., Saint-Jeannet J-P. and Mayor R. (2018). Characterization of Pax3 and Sox10 transgenic Xenopus laevis embryos as tools to study neural crest development. Dev. Biol. 444, S202-S208. 

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Hong C-S. and Saint-Jeannet J-P.(2018). The b-HLH transcription factor Hes3 participates in neural plate border formation by interfering with Wnt/β-catenin signaling. Dev. Biol. 442, 162-172.

 

Nurbaeva M., Eckstein M., Devotta A., Saint-Jeannet J-P., Yule D., Hubbard M. J. and Lacruz R. S. (2018). Evidence that calcium entry into calcium-transporting dental enamel cells is regulated by cholecystokinin, acetylcholine and ATP. Front. Physiol. 9:801. doi: 10.3389/fphys. 2018.00801. 

 

Ossipova O., Kerney R., Saint-Jeannet J-P. and Sokol SY. (2018). Regulation of neural crest development by the formin family protein Daam1. Genesis, 2018;e23108.

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Bae C-J., Hong C-S. and Saint-Jeannet J-P. (2018). Anosmin-1 is essential for neural crest and cranial placodes formation in Xenopus. Biochem. Biophys. Res. Commun. 495, 2257-2263.

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Dubey A., Rose R., Jones D. and Saint-Jeannet J-P. (2018). Generating retinoic acid gradients by local degradation during craniofacial development: one cell’s cue is another cell’s poison. Genesis, 2018;e23091.

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2017

Hong C-S. and Saint-Jeannet J-P. (2017). Znf703, a target of Pax3 and Zic1, regulates neural crest development and hindbrain patterning in Xenopus. Genesis. 2017;e23082.

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Saint-Jeannet J-P. (2017). Whole-mount in situ hybridization of Xenopus embryos. Cold Spring Harb Protoc; doi:10.1101/pdb.prot0972876.

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Dubey A. and Saint-Jeannet J-P. (2017). Modeling human craniofacial disorders in Xenopus. Curr. Pathobiol. Rep. 5, 79-92. doi: 10.1007/s40139-017-0128-8.

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2016

Devotta A., Juraver-Geslin H., Gonzalez, J. A., Hong C-S. and Saint-Jeannet J-P. (2016). Sf3b4-depleted Xenopus embryos: a model to study the pathogenesis of craniofacial defects in Nager syndrome. Dev. Biol. 415, 371-382.

 

2015

Jaurena M. B., Juraver-Geslin H., Devotta A. and Saint-Jeannet J-P. (2015). Zic1 controls placode progenitor formation non-cell autonomously by regulating retinoic acid production and transport. Nat. Commun. 6, 7476 doi: 10.1038/ncomms8476.

 

Bae C-J., Jeong J. and Saint-Jeannet J-P. (2015). A novel function for Egr4 in posterior hindbrain development. Sci. Rep. 5, 7750 doi:10.1038/srep07750.

 

Moody S. A. and Saint-Jeannet J-P. (2015). Development of the pre-placodal ectoderm and cranial sensory placodes. In “Principles of Developmental Genetics”, pp 331-356 (Ed. S. A. Moody). Academic Press.

 

2014

Jeong Y-H, Park B. K. Saint-Jeannet J-P. and Lee Y-H. (2014). Developmental expression of Pitx2c in Xenopus trigeminal and profundal placodes. Int. J. Dev. Biol. 58, 701-704.

 

Hong C-S. and Saint-Jeannet J-P. (2014). Xhe2 is a member of the astacin family of metalloproteases that promotes Xenopus hatching. Genesis 52, 946-951.

 

Hong C-S., Devotta A., Lee Y-H., Park B-Y. and  Saint-Jeannet J-P. (2014). Transcription factor AP2 epsilon (Tfap2e) regulates neural crest specification in Xenopus. Dev. Neurobiol. 74, 894-906.

 

Saint-Jeannet J-P. and Moody S. A. (2014). Establishing the pre-placodal region and breaking it into placodes with distinct identities. Dev. Biol. 389, 13-27.

 

Bae C-J. and Saint-Jeannet J-P. (2014). Induction and specification of neural crest cells: extracellular signals and transcriptional switches. In “Neural Crest Cells: Evolution, Development and Disease”, pp 27-49 (Ed. P. Trainor). Academic Press.

 

Bae C-J., Park B-Y., Lee Y-H., Tobias J. W., Hong C-S. and Saint-Jeannet J-P. (2014). Identification of targets of Pax3 and Zic1 in the developing neural crest. Dev. Biol. 386, 473-483.

 

2013

Lee Y-H., Williams A., Hong C-S., You Y., Senoo M. and Saint-Jeannet J-P. (2013). Early development of the thymus in Xenopus laevis. Dev. Dyn. 242, 164-178.

 

2012

Park B-Y., Hong C-S., Weaver J., Rosocha E. and Saint-Jeannet J-P. (2012). Xaml1/Runx1 is required for the specification of Rohon-Beard sensory neurons in Xenopus. Dev. Biol. 362, 65-75.

 

Chin A. J., Saint-Jeannet J-P. and Lo C. W. (2012). How insights from cardiovascular developmental biology have impacted the care of infants and children with congenital heart disease. Mech. Dev., 129, 75-97.

 

2011

Lee Y-H. and Saint-Jeannet J-P. (2011). Cardiac neural crest is dispensable for outflow tract septation in Xenopus. Development 138, 2025-2034.

 

Lee Y-H. and Saint-Jeannet J-P. (2011). Sox9 function in craniofacial development and disease. Genesis 49, 200-208.

 

2010

Park B-Y. and Saint-Jeannet J-P. (2010). Long-term consequences of Sox9 depletion on inner ear development. Dev. Dyn. 239, 1102-1112.

 

Park B-Y. and Saint-Jeannet J-P. (2010). Expression analysis of Runx3 and other Runx family members during Xenopus development. Gene Exp. Patterns 19, 157-166.

 

Park B-Y. and Saint-Jeannet J-P. (2010). Induction and segregation of the vertebrate cranial placodes. Colloquium Series on Developmental Biology, Vol. 1, No. 3. Morgan & Claypool Publishers.

 

2009

Park B-Y., Hong C-S., Sohail F. A. and Saint-Jeannet J-P. (2009). Developmental expression and regulation of the chemokine CXCL14 in Xenopus. Int. J. Dev. Biol. 53, 535-540.

 

Lee Y-H. and Saint-Jeannet J-P. (2009). Characterization of molecular markers to assess cardiac cushions formation in Xenopus. Dev. Dyn. 238, 3257-3265.

 

2008

Park B-Y. and Saint-Jeannet J-P. (2008). Hindbrain-derived Wnt and Fgf signals cooperate to specify the otic placode in Xenopus. Dev. Biol. 324, 108-121.

 

Hong C-S., Park B-Y. and Saint-Jeannet J-P. (2008). Fgf8a induces neural crest indirectly through the activation of Wnt8 in the paraxial mesoderm. Development 135, 3903-3910.

 

2007

Hong C-S., Park B-Y. and Saint-Jeannet J-P. (2007). The function of Dmrt genes in vertebrate development: it is not just about sex. Dev. Biol. 310, 1-9.

 

Hong C-S. and Saint-Jeannet J-P. (2007). The activity of Pax3 and Zic1 regulates three distinct cell fates at the neural plate border. Mol. Biol. Cell. 18, 2192-2202.

 

2006

O’Donnell, M., Hong C-S., Huang X., Delnicki, R. J. and Saint-Jeannet J-P. (2006). Functional analysis of Sox8 during neural crest development in Xenopus. Development, 133, 3817-3826.

2005

Huang X., Hong C-S., O’Donnell M. and Saint-Jeannet J-P. (2005). The doublesex-related gene, XDmrt4, is required for neurogenesis in the olfactory system. Proc. Natl. Acad. Sci. (USA) 102, 11349-11354.
 

Hong C-S. and Saint-Jeannet J-P. (2005). Sox proteins and neural crest development. Sem. Cell Dev. Biol. 16, 694-703.
 
2004

Saint-Germain N., Lee Y-H., Zhang, Y., Sargent T. D. and Saint-Jeannet J-P. (2004). Specification of the otic placode depends on Sox9 function in Xenopus. Development 131, 1755-1763.

 

Lee Y-H., Aoki Y., Hong C-S., Saint-Germain N., Credidio, C. and Saint-Jeannet J-P. (2004). Early requirement of the transcriptional activator Sox9 for neural crest induction in Xenopus. Dev. Biol. 275, 93-103. 

 

Huang X. and Saint-Jeannet J-P. (2004). Induction of the neural crest and the opportunities of life on the edge. Dev. Biol. 275, 1-11.
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